Nasal and Exhaled Nitric Oxide in Allergic Rhinitis
Clinical and Experimental Otorhinolaryngology
;
: 228-233, 2012.
Article
in English
| WPRIM
| ID: wpr-27073
ABSTRACT
OBJECTIVES:
The primary aim of this study was to assess whether one can use levels of nasal nitric oxide (nNO) and exhaled nitric oxide (eNO) as a means of evaluation in allergic rhinitis.METHODS:
We used a chemiluminescence analyzer to measure nNO and eNO in normal controls (n=34) and allergic rhinitis patients (n=35), and compared these measurements with various parameters of clinical symptoms and laboratory data.RESULTS:
Mean nNO (389+/-119 ppb) in allergic rhinitis patients was significantly higher than normal controls (276+/-88 ppb). Without asthma, mean eNO (64.8+/-55.9 ppb) in allergic rhinitis patients was significantly higher than normal controls (33.0+/-24.0 ppb). In the persistent allergic rhinitis group, eNO concentration was significantly higher, while nNO concentration was significantly lower than the intermittent group.CONCLUSION:
We can use nNO and eNO levels for evaluation of allergic rhinitis. However, we should consider the fact that nNO levels can be reduced, when symptoms are severe and long-lasting. Additionally, in allergic rhinitis, eNO can be elevated without asthma.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Asthma
/
Rhinitis
/
Rhinitis, Allergic, Perennial
/
Luminescence
/
Nitric Oxide
Limits:
Humans
Language:
English
Journal:
Clinical and Experimental Otorhinolaryngology
Year:
2012
Type:
Article
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