CT evolution of nasal steroid management of chronic rhinosinusitis / 中华耳鼻咽喉头颈外科杂志
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
;
(12): 673-678, 2007.
Article
in Chinese
| WPRIM
| ID: wpr-270734
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy of topical steroid treatment of nonpolypoid chronic sinusitis.</p><p><b>METHODS</b>Two cohorts of adult and children with nonpolypoid chronic sinusitis were investigated. The first cohort consisted of 11 pediatric patients [mean age, (11.8 +/- 3.2) years] with a mean Lund score of 10.3 +/- 5.7 (x +/- s). The second cohort consisted of 13 adult patients [mean age, (36.7 +/- 11.0) years] with a mean Lund score of 12.2 +/- 5.7. The mean duration of the nasal budesonide (Rhinocort) treatment was (7.5 +/- 3.2) weeks for adult patients (256 microg/d) and (7.0 +/- 3.4) weeks for pediatric patients (128 microg/d). Each Lund score and the patient's assessment of nasal symptoms were evaluated after treatment.</p><p><b>RESULTS</b>The average Lund score was significantly decreased to 6.5 -/+ 7.5 (t = 3.82, P < 0.01) in adult patients and to 2.6 +/- 3.7 (t = 5.08, P < 0.01) in pediatric patients after treatment. Thirty-eight percent of the adult patients and 73% of the pediatric patients were cured on CT images. The patient's self-assessment of efficacy was positively correlated with pretreatment Lund score in adult patients (r = 0.676, P < 0.05), but not so in pediatric patients.</p><p><b>CONCLUSIONS</b>These findings demonstrate that most of patients with nonpolypoid chronic sinus did well with topical steroid treatment. Therefore, surgery was required in few patients.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Paranasal Sinuses
/
Sinusitis
/
Steroids
/
Diagnostic Imaging
/
Tomography, X-Ray Computed
/
Chronic Disease
/
Treatment Outcome
/
Therapeutic Uses
/
Drug Therapy
Type of study:
Diagnostic study
Limits:
Adolescent
/
Adult
/
Child
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Year:
2007
Type:
Article
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