Endotoxins in the prostatic secretions of chronic prostatitis patients / 亚洲男科学杂志(英文版)
Asian Journal of Andrology
;
(6): 45-47, 2005.
Article
in English
| WPRIM
| ID: wpr-270874
ABSTRACT
<p><b>AIM</b>To evaluate the clinical significance of the quantitative determinations of endotoxins in the expressed prostatic secretions (EPS) of chronic prostatitis (CP) patients.</p><p><b>METHODS</b>The EPS of 45 patients with CP and 15 normal volunteers were obtained for microscopic examination, bacterial culture and endotoxin determination. The level of endotoxins was determined by the Limulus-amebocyte-lysate test with chromogenic substrate.</p><p><b>RESULTS</b>Patients with CP had higher mean levels of endotoxins in EPS than normal volunteers [52.06 +/- 32.83 EU/L vs. 4.77 +/- 4.14 EU/L (P <0.05)]. The levels of endotoxins in CP type II, type IIIa and type IIIb were 68.62 +/- 34.78 EU/L, 45.30 +/- 23.33 EU/L and 15.83 +/- 5.31 EU/L, respectively [type II vs. type IIIa (P >0.05), type IIIb vs. normal controls (P <0.05), type II/type IIIa vs. normal controls P >0.05)].</p><p><b>CONCLUSION</b>CP patients have elevated levels of endotoxins in the EPS, which suggests that inflammation is a feature of this disease. EPS endotoxin determination is not only helpful in diagnostic confirmation, but also in evaluating the response to treatment in CP patients.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prostate
/
Prostatitis
/
Bacterial Infections
/
Case-Control Studies
/
Chronic Disease
/
Sensitivity and Specificity
/
Bodily Secretions
/
Diagnosis
/
Endotoxins
/
Metabolism
Type of study:
Diagnostic study
/
Observational study
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
Asian Journal of Andrology
Year:
2005
Type:
Article
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