A Case of Hypereosinophilic Syndrome with Bladder Involvement in a 7-Year-Old Boy
Childhood Kidney Diseases
;
: 167-170, 2015.
Article
in English
| WPRIM
| ID: wpr-27103
ABSTRACT
Hypereosinophilic syndrome (HES) is characterized by the presense of hypereosinophilia with evidence of target organ damage. We report a patient diagnosed with eosinophilic cystitis and HES. A 7 year old boy had hematuria, dysuria, and increased urinary frequency for 1 day. Laboratory examinations revealed hypereosinophilia (eosinophils, 2,058/microL), hematuria, and proteinuria. Abdominal sonography revealed diffuse and severe wall thickening of the bladder. The patient was treated initially with antibiotics. However, his symptoms did not improve after 7 days. A computed tomography scan demonstrated severe wall thickening of the bladder and the hypereosinophilia persisted (eosinophils, 2,985/microL). The patient complained of chest discomfort, dyspnea, epigastric pain, and vomiting on hospital day 10. Parasitic, allergic, malignancy, rheumatologic, and immune workups revealed no abnormal findings. Chest X-rays, electrocardiography, and a pulmonary function test were normal; however, the hypereosinophilia was aggravated (eosinophils, 3,934/microL). Oral deflazacort was administered. A cystoscopic biopsy showed chronic inflammation with eosinophilic infiltration. The patient's respiratory, gastrointestinal, and urinary symptoms improved after 6 days of steroids, and he was discharged. The eosinophil count decreased dramatically (182/microL). The hypereosinophilia waxed and waned for 7 months, and the oral steroids were tapered and stopped. This case describes a patient diagnosed with eosinophilic cystitis and HES.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Proteinuria
/
Respiratory Function Tests
/
Steroids
/
Thorax
/
Vomiting
/
Biopsy
/
Urinary Bladder
/
Hypereosinophilic Syndrome
/
Cystitis
/
Dyspnea
Limits:
Child
/
Humans
/
Male
Language:
English
Journal:
Childhood Kidney Diseases
Year:
2015
Type:
Article
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