Treatment of superficial infantile hemangiomas with topical propranolol / 中华整形外科杂志
Chinese Journal of Plastic Surgery
;
(6): 100-103, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-271223
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy and safety of 1% propranolol ointment in the treatment of superficial infantile hemangiomas (IHs).</p><p><b>METHODS</b>A retrospective chart review was performed on 49 children (34 female and 15 male) with a median age of 4.1 months (range, 1-10 months). A total of 58 superficial IHs were treated with 1% propranolol ointment. Topical propranolol was applied three times daily for a mean duration of 21.1 weeks (range, 5-59 weeks). Changes in the size, texture, and color of the tumor were monitored and recorded at regular intervals. The treatment response was evaluated using a 3-point scale system good, partial, and no response. Adverse effects after medication were evaluated and managed accordingly.</p><p><b>RESULTS</b>Of the 49 cases, 26 (53.1%) demonstrated good response, 17 (34.7%) showed a partial response, and 6 (12.2%) had no response. The total effective rate was 87.8% . No systemic complication was observed in any of the patients.</p><p><b>CONCLUSIONS</b>Topical therapy with 1% propranolol ointment may be a safe and effective method for the treatment of superficial IHs and can be used as an adjuvant treatment measure during the wait-and-see period.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ointments
/
Propranolol
/
Skin Neoplasms
/
Treatment Outcome
/
Therapeutic Uses
/
Drug Therapy
/
Hemangioma
Limits:
Female
/
Humans
/
Infant
/
Male
Language:
Chinese
Journal:
Chinese Journal of Plastic Surgery
Year:
2013
Type:
Article
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