Effect of propranolol gel on infantile hemangiomas / 中华整形外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the efficacy and security of propranolol gel in treatment of Infantile hemangiomas.</p><p><b>METHODS</b>51 consecutive infants with hemangiomas from October 2010 to September 2011 in Department of General Surgery Fuzhou General Hospital of Nanjing Military Command were treated with propranolol hydrochloride 3% gel. Changes in hemangioma size, texture, color, tumor blood flow peak were recorded.</p><p><b>RESULTS</b>The results were evaluated using Achauer system, responses of IHs to propranolol were considered scale I (poor) in 4 patient (17.24%), scale II (moderate) in 18 patients (24.14%), scale III (good) in 22 patients (44.83%) and scale IV (excellent) in 7 patients (13.79%). The response of superficial hemangiomas was significantly better than other hemangiomas (P < 0.05), and no significant differences in response among different primary sites (P > 0.05).</p><p><b>CONCLUSIONS</b>Topical use of propranolol hydrochloride 3% gel is an effective option for superficial hemangiomas.</p>