Saponins of polygalacic acid type from Platycodon grandiflorum / 药学学报
Acta Pharmaceutica Sinica
; (12): 358-360, 2006.
Article
in Zh
| WPRIM
| ID: wpr-271427
Responsible library:
WPRO
ABSTRACT
<p><b>AIM</b>To isolate triterpene saponins of polygalacic acid type from the roots of Platycodon grandiflorum (Jacq.) A. DC and to identify their structures.</p><p><b>METHODS</b>The compounds were separated by means of extraction, chromatography on silica gel, MPLC and HPLC, and their structures were elucidated on the basis of spectral analyses (FAB-MS, IR, 1H NMR, 13C NMR etc.).</p><p><b>RESULTS</b>Three triterpene saponins were isolated from the roots of Platycodon grandiflorum. They were identified as 3-O-beta-D-laminaribiosyl polygalacic acid (I), 3-O-beta-D-glucopyranosyl polygalacic acid (II), polygalacin D (III), separately.</p><p><b>CONCLUSION</b>Compound I is a new compound, compounds II, III are known triterpene saponins. The compound I and II were isolated from the plant for the first time, which is also the monodesmoside from the plant for the first time.</p>
Full text:
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Index:
WPRIM
Main subject:
Plants, Medicinal
/
Saponins
/
Molecular Structure
/
Chemistry
/
Plant Roots
/
Platycodon
/
Molecular Conformation
Language:
Zh
Journal:
Acta Pharmaceutica Sinica
Year:
2006
Type:
Article