Tacrolimus ointment: An Open study for Effects on Severe Facial Atopic Dermatitis in Korean
Annals of Dermatology
;
: 195-199, 2002.
Article
in English
| WPRIM
| ID: wpr-27220
ABSTRACT
BACKGROUND:
In recent studies, tacrolimus ointment has been shown to be effective for the treatment of atopic dermatitis with an excellent safety profile.OBJECTIVE:
This study was done to assess the efficacy and side-effects of tacrolimus ointment for the facial atopic dermatitis(AD) in Korean. PATIENTS ANDMETHODS:
Open-label, non-comparative study with 2 months' follow-up was done to assess the efficacy and safety of tacrolimus ointment (Protopic0ointment 0.1%, Fujisawa, Japan) in moderate to severe facial AD. Patients were instructed to apply it two times daily for 8 weeks. Facial lesions were evaluated at baseline, 4 and 8 weeks of treatment with in-tensity score by investigator.RESULTS:
In comparing of intensity scores and each clinical score at baseline with those of 4 and 8 weeks of treatment, a significant decrease was noticed at all follow-up periods. Burning sense(54.5%) and pruritus(18.2%) were detected.CONCLUSION:
Tacrolimus ointment is effective in treatment of severe facial AD and has tolerable mild adverse effects at the site of application in Korean.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Research Personnel
/
Burns
/
Follow-Up Studies
/
Tacrolimus
/
Dermatitis, Atopic
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Annals of Dermatology
Year:
2002
Type:
Article
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