Low ankle brachial index and risk of death: a meta-analysis / 中华心血管病杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the association between low ankle brachial index and risk of death.</p><p><b>METHODS</b>Related cohort studies in the past 12 years were collected. Heterogeneity was analyzed with χ(2) and I(2). Pooled hazard ratio (HR) as the effect indicator and 95% confidence interval (CI) were used to estimate the association of low ankle brachial index and risk of death by fixed effect model (inverse variance method).</p><p><b>RESULTS</b>A total of 8 studies were included with sum sample size of 30 029. In heterogeneity analysis, χ(2) was 5.46, I(2) was 0.0%, and P was 0.604. Meta-analysis resulted in pooled HR of 1.69 (95%CI 1.55 - 1.84).</p><p><b>CONCLUSION</b>Low ankle brachial index is associated with increased risk of death.</p>