Pathogenesis and Prevention of Transfusion-Associated Graft-versus-Host Disease / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1774-1779, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-272523
ABSTRACT
Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare complication of blood transfusion. The disease is fulminant and fatal in most patients. TA-GVHD is caused by transfused alloreactive donor T lymphocytes that attack host tissue, including skin, liver, gastrointestinal tract and bone marrow. Most patients are immunocompromised, but immunocompetent patients can also be involved. Irradiation of blood components is generally recommended to prevent the onset of TA-GVHD for susceptible recipients. This review focus on pathogenesis and prevention of TA-GVHD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Tissue Donors
/
Blood Transfusion
/
Bone Marrow
/
T-Lymphocytes
/
Gastrointestinal Tract
/
Graft vs Host Disease
/
Liver
Type of study:
Etiology study
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2015
Type:
Article
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