R ± BEACOP for Treating Newly Diagnosed, Moderate and High Risk Diffuse Large B Cell Lymphoma Patients / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1591-1595, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-272555
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy and safety of R ± BEACOP protocol on newly diagnosed patients with moderate and high risk diffuse large B-cell lymphoma (DLBCL).</p><p><b>METHODS</b>The clinical data of 19 newly diagnosed patients with moderate and high risk DLBCL received at least 2 cycles of R ± BEACOP protocol during 2011 to 2014 were collected, their therapeutic efficacy and side effects were evaluated by retrospective analysis.</p><p><b>RESULTS</b>The overall response rate of 19 assessable patients was 94.7%, including 5 patients (26.3%) in complete remission (CR) and 13 patients (68.4%) in partial remission (PR). The major toxicity was hematologic toxicity and the incidence of grade III-IV hematologic toxicity was 73.7%. Other toxicities were mild and no treatment-related death occurred.</p><p><b>CONCLUSION</b>R ± BEACOP protocol is a effective and safe protocol for the patients with DLBCL which is worth further multicenter prospectively studying in china.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Remission Induction
/
Antineoplastic Combined Chemotherapy Protocols
/
China
/
Retrospective Studies
/
Lymphoma, Large B-Cell, Diffuse
Type of study:
Etiology study
/
Practice guideline
/
Observational study
Limits:
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2015
Type:
Article
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