Tumor multidrug-resistance and reversing actions of traditional Chinese medicine / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 828-830, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-272792
ABSTRACT
Tumor multidrug-resistance (MDR) is a major factor in chemotherapeutic failure. In recent years, the development of anti-MDR has become an important focus in research. The mechanisms of MDR relate to P-glycoprotein, MRP1, apoptosis, the unusual DNA repair, the organic micro-environment, and so on. This review summarized the advances in MDR mechanism research. At the same time, it summarized the recent research of traditional Chinese medicine in reversing MDR. Furthermore, their mechanisms and major features of actions were also discussed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Drugs, Chinese Herbal
/
Gene Expression Regulation, Neoplastic
/
Apoptosis
/
ATP Binding Cassette Transporter, Subfamily B, Member 1
/
Drug Resistance, Multiple
/
Drug Resistance, Neoplasm
/
Multidrug Resistance-Associated Proteins
/
Cell Line, Tumor
/
DNA Repair
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2004
Type:
Article
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