Experimental study on anti-pyretic effect of gegen qin lian decoction and its compounds / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 663-666, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-272828
ABSTRACT
<p><b>OBJECTIVE</b>To investigate composition principles of Gegen Qin Lian decoction through anti-pyretic experiment.</p><p><b>METHOD</b>Pharmacological effects of different compounds of Gegen Qin Lian decoction according to six hours temperature response index (TRI6) and average top temperature response height (deltaT) after the decoction was given to feverish animal model by inactived bacteria suspension.</p><p><b>RESULT</b>As for reducing six hour temperature response index, Scutellaria baicalensis root was the main effective drug. Pueraria lobata root could enforce the effect while Coptis chinensis rhizome and Glycyrrhiza uralensis root counteracted it. As for reducing average top temperature response height, the Effects of four herbal drugs were the same as for TRI6.</p><p><b>CONCLUSION</b>Of the compounds of Gegen Qin Lian decoction, as to the pharmcological anti-pyretic effects, the best one is the compound of Scutellaria baicalensis and Pueraria lobata roots.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Plants, Medicinal
/
Drugs, Chinese Herbal
/
Chemistry
/
Rats, Wistar
/
Plant Roots
/
Analgesics, Non-Narcotic
/
Glycyrrhiza uralensis
/
Pueraria
/
Scutellaria baicalensis
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2004
Type:
Article
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