Study on the healing effect of pneumoconiosis with tetrandrine and massive whole-lung lavage / 中华劳动卫生职业病杂志
Chinese Journal of Industrial Hygiene and Occupational Diseases
;
(12): 68-70, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-273545
ABSTRACT
<p><b>OBJECTIVE</b>To study the healing effect of pneumoconiosis with tetrandrine and massive whole-lung lavage.</p><p><b>METHODS</b>Choose 34 confirmed pneumoconiosis patients as drug treatment group and complex treatment group, and 17 tested workers as control group. Collected the content of TGF-beta1 and P III P which in these three investigated groups.</p><p><b>RESULTS</b>Drug treatment group and complex treatment group of patients improved the clinical symptoms and lung function Compared with Pretreatment, the FVC, FEV1.0, FEV1.0/FVC, MVV was obviously higher than those before treatment (P < 0.05). Complex treatment group than in the drug treatment group increased more significantly (P < 0.05). The level of TGF-beta1 and P III P was reduced after complex treatment (P < 0.05). Moreover,the level of TGF-beta1 and P III P in these patients are lower than in those patients treated with tetrandrine combined with whole lung lavage (P < 0.05).</p><p><b>CONCLUSION</b>Tetrandrine combined with whole-lung lavage could significantly retard the development of pneumoconiosis by lessening the TGF-beta1 and P III P in serum.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumoconiosis
/
Therapeutics
/
Blood
/
Treatment Outcome
/
Combined Modality Therapy
/
Bronchoalveolar Lavage
/
Collagen Type III
/
Benzylisoquinolines
/
Therapeutic Uses
/
Transforming Growth Factor beta1
Limits:
Adult
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Industrial Hygiene and Occupational Diseases
Year:
2012
Type:
Article
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