Direct determination of 21 elements in serum by dynamic reaction cell inductively coupled plasma mass spectrometry / 中华劳动卫生职业病杂志

ABSTRACT

<p><b>OBJECTIVE</b>To establish a method to directly determine 21 elements in serum by dynamic reaction cell inductively coupled plasma mass spectrometry (DRC-ICP-MS).</p><p><b>METHODS</b>The serum samples were diluted with 1% nitric acid by 3 times. The inductively coupled plasma mass spectrometry (ICP-MS) was used simultaneously to detect the serum concentrations of 21 elements (Be, Al, Mn, V, Cr, Fe, Co, Ni, Cu, Zn, As, Se, Mo, Ag, Cd, Sb, Ba, T1, Ph, Th, U).</p><p><b>RESULTS</b>The detection limits of all elements were between 0.001-0.0711 g/1. Standard linear correlation coefficients (r) were 50.999. Standard deviations were less than 5%,the recovery rates were 90%-114%. Standard reference materials were used for quality control standards and the analysis results conformed with the certified values.</p><p><b>CONCLUSION</b>The present method is a simple, rapid,sensitive and accurate method for detecting the serum samples.</p>