The association of cardiovascular disease with impaired health-related quality of life among patients with type 2 diabetes mellitus
Singapore medical journal
;
: 209-216, 2014.
Article
in English
| WPRIM
| ID: wpr-274255
ABSTRACT
<p><b>INTRODUCTION</b>The aim of this study was to evaluate the health-related quality of life (HRQoL) of Malaysian patients with type 2 diabetes mellitus (T2DM) who have cardiovascular disease (CVD), as well as identify the determinants of HRQoL among this cohort of patients.</p><p><b>METHODS</b>This study was an analytical cross-sectional study involving 313 patients aged 30-78 years (150 men, 163 women; mean age 55.7 ± 9.2 years) who were diagnosed with T2DM (mean duration of T2DM 10.1 ± 8.1 years) at two tertiary Malaysian government hospitals. The patients' sociodemographic, lifestyle, clinical and laboratory data were collected prospectively from medical records and via face-to-face interviews. HRQoL was assessed using the 15D instrument - a generic, 15-dimensional and standardised measure of HRQoL that can be used as both a profile and a single index score measure.</p><p><b>RESULTS</b>T2DM patients with CVD were found to have significantly lower 15D HRQoL scores than their nonCVD counterparts (p < 0.001). The HRQoL of T2DM patients with CVD was significantly lower than those without CVD (p < 0.05) in all of the 15 dimensions of the 15D instrument. Multinomial logistic regression analysis using backward stepwise method revealed a significant association between CVD and impaired HRQoL (odds ratio [OR] 11.746, 95% confidence interval [CI] 4.898-28.167). Age (OR 1.095, 95% CI 1.054-1.137), duration of T2DM (OR 1.085, 95% CI 1.032-1.140), ethnicity (OR 0.411, 95% CI 0.187-0.903), body mass index (OR 1.074, 95% CI 1.006-1.148), and physical activity level (OR 3.506, 95% CI 1.415-8.689) were also significant predictors of HRQoL.</p><p><b>CONCLUSION</b>In T2DM patients, the presence of CVD was significantly associated with a lower HRQoL. Therefore, the importance of tertiary prevention to minimise the potential deterioration of the HRQoL of T2DM patients with CVD should be highly emphasised.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Psychology
/
Quality of Life
/
Social Class
/
Cardiovascular Diseases
/
Cross-Sectional Studies
/
Surveys and Questionnaires
/
Diabetes Mellitus, Type 2
/
Tertiary Care Centers
/
Malaysia
Type of study:
Observational study
/
Prevalence study
/
Prognostic study
/
Qualitative research
/
Risk factors
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Singapore medical journal
Year:
2014
Type:
Article
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