Hyponatremia in Children with Central Nervous System Infections
Journal of the Korean Child Neurology Society
;
: 143-151, 2013.
Article
in Korean
| WPRIM
| ID: wpr-27426
ABSTRACT
PURPOSE:
To compare the effect of different etiologies in children with central nervous system (CNS) infections on the incidence of initial and hospital-acquired hyponatremia (IH and HAH) (plasma sodium concentration, PNa or =0.45% saline in dextrose.RESULTS:
Of 244 children with CNS infections (group A 185, group B 33, group C 23, and group D 3), 55 patients (22.5%) revealed IH- or HAH-hyponatremia. IH and HAH was found in 13.1% (32/244) and 9.4% (23/244), respectively. The incidence of IH was significantly higher in group-C (30.4%, P=0.010) than in group-A (9.2%) or group-B (21.2%). HAH was more frequent in group-B (27.3%, P<0.001) and in group-D (66.7%, P=0.001) than in group-A (4.9%) or in group-C (13.0%). Of the patients in group-I, 28.6% (8/28) developed more common HAH compared with 6.9% (15/216) of children in group-II (P<0.001).CONCLUSION:
IH and HAH were relatively common in children with CNS infections and their incidences were distinctly different among patients from different etiologies. It seems that the administration of hypertonic saline can help to reduce the incidence of HAH among children with CNS infections. election.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sodium
/
Tuberculosis, Meningeal
/
Central Nervous System
/
Central Nervous System Infections
/
Incidence
/
Retrospective Studies
/
Meningitis, Bacterial
/
Glucose
/
Hyponatremia
/
Meningitis
Type of study:
Incidence study
/
Observational study
/
Prognostic study
Limits:
Child
/
Humans
Language:
Korean
Journal:
Journal of the Korean Child Neurology Society
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS