Determination of doping in human urine by gas chromatography-high resolution mass spectrometry / 药学学报
Acta Pharmaceutica Sinica
;
(12): 1667-1670, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-274606
ABSTRACT
A method was evaluated for determination of twenty-one doping (including nandrolone, boldenone and methandienone) in human urine by gas chromatography-high resolution mass spectrometry. Samples were prepared by liquid-liquid extraction, concentrated, TMS derivatization and limit of detection at ng x mL(-1) by MID/GC/HRMS. According to the code of the World Anti-Doping Agency (WADA), precision and recoveries of the procedure were evaluated by replicate analysis (n = 6), the recoveries in the range of 66%-103%, with the RSD below 10.0%. The precision within the day of the method with three different concentrations was also determined RSD were less than 9.5%, 10.0% and 9.7%.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Testosterone
/
Urine
/
Substance Abuse Detection
/
Doping in Sports
/
Anabolic Agents
/
Gas Chromatography-Mass Spectrometry
/
Methandrostenolone
/
Methods
/
Nandrolone
Limits:
Humans
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS