Effect of Preventive Nicardipine on Hemodynamics Induced by Pneumoperitoneum during Laparoscopic Cholecystectomy / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 327-331, 2005.
Article
in Korean
| WPRIM
| ID: wpr-27471
ABSTRACT
BACKGROUND:
Pneumoperitoneum for a laparoscopic cholecystectomy induces hemodynamic changes. The present study investigated the effect of preventive nicardipine on the hemodynamics induced by pneumoperitoneum during a laparoscopic cholecystectomy.METHODS:
Forty five patients, scheduled to undergo laparoscopic cholecystectomy, were selected, and divided into three groups; the control group (C; normal saline infusion), the nicardipine bolus injection group (NB; 20microgram/kg nicardipine infusion, 1 min before skin incision) and the nicardipine continuous infusion group (NI; 2microgram/kg/min continuous infusion, from the time of endotracheal intubation to pneumoperitoneum). The blood pressure, heart rate, cardiac output and systemic vascular resistance were measured; at preincision, and at 5, 10 and 15 min after insufflation and at 5 min after exsufflation.RESULTS:
Nicardipine injection attenuated increases in the blood pressure, systemic vascular resistance after pneumoperitoneum, and didn't attenuate decrease in the cardiac output.CONCLUSIONS:
A preventive nicardipine injection is effective in attenuating the hemodynamic change after pneumoperitoneum during a laparoscopic cholecystectomy, especially attenuated the systemic vascular resistance and blood pressure increase.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pneumoperitoneum
/
Skin
/
Vascular Resistance
/
Blood Pressure
/
Cholecystectomy
/
Insufflation
/
Cardiac Output
/
Nicardipine
/
Cholecystectomy, Laparoscopic
/
Laparoscopy
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
2005
Type:
Article
Similar
MEDLINE
...
LILACS
LIS