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Comparison of dobutamine stress echocardiography and exercise echocardiography in evaluating left ventricular outflow tract obstruction in patients with hypertrophic cardiomyopathy / 中华心血管病杂志
Chinese Journal of Cardiology ; (12): 214-218, 2012.
Article in Chinese | WPRIM | ID: wpr-275073
Responsible library: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To compare left ventricular outflow tract (LVOT) gradient induced by dobutamine stress echocardiography (DSE) and exercise echocardiography (EE) in patients with hypertrophic cardiomyopathy (HCM).</p><p><b>METHODS</b>DSE and EE were performed in 40 consecutive patients with HCM and LVOT gradient < 50 mm Hg (1 mm Hg = 0.133 kPa) at rest. Dobutamine was administered intravenously at incremental doses of 200, 400, 600, 800 and 1200 µg/min at 5 min intervals. LVOT gradients were measured at rest, at peak exercise and during each dose of DSE.</p><p><b>RESULTS</b>LVOT gradient at rest was lower than 30 mm Hg in 36 patients and between 30 and 49 mm Hg in 4 patients. Of the 36 patients with LVOT gradient < 30 mm Hg at rest, mechanical LVOT obstruction (latent LVOTO) was evidenced in 17 patients during EE and in 18 patients during DSE and good consistency (91.7%, kappa value 0.833) was found between the two maneuvers. The provoked gradient was similar between DSE at 800 µg/min and EE at peak exercise (P = 0.181). In the 4 patients with LVOT gradient between 30 and 49 mm Hg [(38.8 ± 2.6) mm Hg], LVOT gradient increased to (85.3 ± 26.4) mm Hg during EE and (105.0 ± 28.0) mm Hg during DES.</p><p><b>CONCLUSIONS</b>DES and EE are comparable and suitable provoke methods for identifying LVOT obstruction in patients with HCM.</p>
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Cardiomyopathy, Hypertrophic / Female / Humans / Male / Diagnostic Imaging / Ventricular Outflow Obstruction / Adult / Echocardiography, Stress / Exercise Test / Methods Language: Chinese Journal: Chinese Journal of Cardiology Year: 2012 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Cardiomyopathy, Hypertrophic / Female / Humans / Male / Diagnostic Imaging / Ventricular Outflow Obstruction / Adult / Echocardiography, Stress / Exercise Test / Methods Language: Chinese Journal: Chinese Journal of Cardiology Year: 2012 Type: Article