Clone of M2 autoantigens from human sources and evaluation of measurement of M2 autoantibodies in diagnosis of primary biliary cirrhosis / 中华肝脏病杂志
Chinese Journal of Hepatology
;
(12): 341-343, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-276575
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the value of measurement of M2 autoantibodies in diagnosis of primary biliary cirrhosis (PBS).</p><p><b>METHODS</b>M2 autoantibodies were detected by ELISA combined with western-blot.</p><p><b>RESULTS</b>Thirty-two cases presented positive M2 autoantibodies, including 20 cases of PBC, 9 liver diseases of unknown etiology, 1 autoimmune hepatitis and 1 drug-induced liver injury.</p><p><b>CONCLUSIONS</b>M2 autoantibodies show good sensitivity and specificity to diagnosis of PBC. It should be used as a powerful and specific maker for the diagnosis of PBC</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Autoantibodies
/
Autoantigens
/
Enzyme-Linked Immunosorbent Assay
/
Sensitivity and Specificity
/
Hepatitis, Autoimmune
/
Diagnosis
/
Allergy and Immunology
/
Chemical and Drug Induced Liver Injury
/
Liver Cirrhosis, Biliary
Type of study:
Diagnostic study
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Hepatology
Year:
2002
Type:
Article
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