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Comparison of Non-invasive Imaging Studies in the Evaluation of Carotid Artery Stenosis and Occlusion: CT Angiography, Time-of-Flight MR Angiography and Contrast-Enhanced MR Angiography
Journal of the Korean Society of Magnetic Resonance in Medicine ; : 234-241, 2011.
Article in Korean | WPRIM | ID: wpr-27666
ABSTRACT

PURPOSE:

We compared non-invasive imaging studies of CTA, TOF-MRA and CE-MRA to evaluate detecting internal carotid artery stenosis and occlusion. MATERIALS AND

METHODS:

We enrolled 20 patients with clinically suspected internal carotid artery stenosis and occlusion, or asymptomatic patient with more than 50% stenosis suspected on color Doppler ultrasonography for regular check-up. Prospectively, CTA, TOF-MRA and CE-MRA were performed, and sensitivity, specificity, positive predictive value, negative predictive value and accuracy of TOF-MRA and CE-MRA using CTA as a reference standard for detecting more than 50% stenosis were evaluated, and correlations of measured percent stenosis between 3 imaging studies were also evaluated.

RESULTS:

No significant difference was found between 3 imaging studies in measuring stenosis(p>0.05). Correlation coefficient was 0.932 between CTA and TOF-MRA, and 0.971 between CTA and CE-MRA. TOF-MRA had 83.3% sensitivity, 87.5% specificity, 71.4% positive predictive value, 93.3% negative predictive value and 86.4% accuracy for detecting more than 50% stenosis and occlusion. CE-MRA had 83.3% sensitivity, 93.8% specificity, 83.3% positive predictive value, 93.8% negative predictive value and 90.9% accuracy.

CONCLUSION:

TOF-MRA and CE-MRA provided high correlations in the evaluation of internal carotid artery stenosis and occlusion.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Angiography / Carotid Arteries / Prospective Studies / Sensitivity and Specificity / Carotid Stenosis / Ultrasonography, Doppler, Color / Constriction, Pathologic Type of study: Diagnostic study / Observational study Limits: Humans Language: Korean Journal: Journal of the Korean Society of Magnetic Resonance in Medicine Year: 2011 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Angiography / Carotid Arteries / Prospective Studies / Sensitivity and Specificity / Carotid Stenosis / Ultrasonography, Doppler, Color / Constriction, Pathologic Type of study: Diagnostic study / Observational study Limits: Humans Language: Korean Journal: Journal of the Korean Society of Magnetic Resonance in Medicine Year: 2011 Type: Article