Contemporary clinical trials in uterine corpus malignancies / 대한산부인과학회지

ABSTRACT

Uterine cancer is the most common gynecologic malignancy in Western countries. In Korea, its incidence has been rising, and the increased incidence is associated with a rising death rate. The first two decades of endometrial cancer study by the GOG began with a prospective, surgicopathologic staging trial that was the cornerstone for development of all subsequent trials. The therapeutic strategies were tailored to disease extent - low risk, intermediate risk, and high risk groups of patients. There were great advances in the area of chemotherapeutic agents through a number of extensive phase II trials. New trials of these agents have been opened for the patients with advanced or recurrent uterine cancers.