Piggy-back liver transplantation in treating acute liver failure patients: a report of 15 cases / 中华肝脏病杂志
Chinese Journal of Hepatology
;
(12): 49-52, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-277612
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinical significance of piggy-back liver transplantation in treating acute liver failure (ALF).</p><p><b>METHODS</b>Fifteen ALF patients (13 caused by HBV and 2 with acute Wilson disease) had piggy-back liver transplantations (PBLT) in our hospital from Sept 1999 to Feb 2006. The outcomes of these patients were retrospectively analyzed.</p><p><b>RESULTS</b>One year survival rate of the 15 patients was 87% (13/15). Excellent outcome was achieved in the 2 acute Wilson disease cases their corneal Kayser-Fleischer rings disappeared and serum ceruloplasmin levels returned to normal. Among the 15 cases, one died of severe pulmonary infection and another died of multiple organ system failure on the 6th and 11th postoperative days. HBsAg positivity was observed in 13 cases before liver transplantation. Eleven patients survived and later received anti-HBV treatment recommended by the American Association for the Study of Liver Diseases. Their HBsAg became negative.</p><p><b>CONCLUSION</b>Liver transplantation is an effective therapy for ALF and can improve survival rate significantly.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
General Surgery
/
Survival Rate
/
Retrospective Studies
/
Mortality
/
Liver Transplantation
/
Liver Failure, Acute
/
Methods
Type of study:
Observational study
/
Prognostic study
Limits:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Chinese Journal of Hepatology
Year:
2008
Type:
Article
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