Design and synthesis of a type of benzopyran derivatives with insulin-sensitizing activity / 药学学报
Acta Pharmaceutica Sinica
;
(12): 605-610, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-277788
ABSTRACT
Ten novel compounds were designed and synthesized on the basis of compound 1, their insulin-sensitizing activities were evaluated in 3T3-L1 cells. Results showed that compound 10 exhibited strong differentiation-stimulating activity on 3T3-L1 cells model, which indicated that compound 10 may possess well insulin-sensitizing activity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Benzopyrans
/
Drug Design
/
3T3-L1 Cells
/
Hypoglycemic Agents
/
Insulin
Limits:
Animals
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2008
Type:
Article
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