Advance of several types of important marine antitumor drugs

Jian-Ye ZHANG; Li-Wu FU; Jian-Ye ZHANG; Li-Wu FU

Advance of several types of important marine antitumor drugs / 药学学报

Jian-Ye ZHANG; Li-Wu FU; Jian-Ye ZHANG; Li-Wu FU.

Acta Pharmaceutica Sinica ; (12): 435-442, 2008.

Article in Chinese | WPRIM | ID: wpr-277834

ABSTRACT

ABSTRACT

Marine antitumor drugs have been the research focus in the world. Recently, advancement has been made in the investigation of six types of compounds including bryostatin-1, ecteinascidin-743, dolastatin, didemnin B, psammaplin and halichondrin B. In this review, we summarized the recent research progress of the above mentioned marine antitumor drugs and their derivatives. Also, the development tendency of marine antitumor drugs was discussed.

Subject(s)

Animals; Humans; Antineoplastic Agents; Pharmacology; Therapeutic Uses; Apoptosis; Biological Products; Pharmacology; Therapeutic Uses; Bryostatins; Pharmacology; Therapeutic Uses; Cell Line, Tumor; Depsipeptides; Pharmacology; Therapeutic Uses; Dioxoles; Pharmacology; Therapeutic Uses; Disulfides; Pharmacology; Ethers, Cyclic; Pharmacology; Macrolides; Marine Biology; Neoplasms; Drug Therapy; Pathology; Tetrahydroisoquinolines; Pharmacology; Therapeutic Uses; Tyrosine; Pharmacology

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Pharmacology / Tyrosine / Biological Products / Apoptosis / Macrolides / Cell Line, Tumor / Tetrahydroisoquinolines / Therapeutic Uses / Depsipeptides Limits: Animals / Humans Language: Chinese Journal: Acta Pharmaceutica Sinica Year: 2008 Type: Article

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