Risk Factors and Prognosis of Reintubation Following Surgeries under General Anesthesia / 中国医学科学院学报

ABSTRACT

Objective To investigate the independent risk factors and the prognosis of reintubation following surgeries under general anesthesia in post-anesthesia care unit (PACU). Methods 　We retrospectively analyzed the clinical data of 14 407 patients undergoing elective surgeries from October 2013 to October 2014 in the China-Japanese Friendship Hospital. Patients were divided into reintubation group and control group according to the application of reintubation (or not) in PACU. Multivariate Logistic analysis was performed for factors showing significant difference between these two groups to screen for risk factors and analyze the prognosis. Results 　Sixteen patients (0.11%) were reintubated in PACU.The Logistic regression analysis showed that the independent risk factors for reintubation were as followingpreoperative chronic obstructive pulmonary disease (COPD)(OR=17.55,95%CI3.08-59.84,P=0.001) or preoperative coronary artery disease (OR=5.98,95%CI1.67-21.42,P=0.006),intraoperative blood loss greater than 12 ml·kg-1 (OR=27.83,95%CI10.75-54.62,P <0.001),and thoracic surgery (OR=22.96,95%CI12.66-48.19,P=0.004). Conclusion s　Preoperative COPD or coronary artery disease,intraoperative blood loss greater than 12 ml·kg-1,and thoracic surgery are the independent risk factors for postoperative PACU reintubation of patients undergoing surgeries with general anesthesia.Although the mortality rate is relative high,most patients have a good prognosis.