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Advances in Evaluation of Cognitive Impairment in Patients with Cushing's Disease / 中国医学科学院学报
Acta Academiae Medicinae Sinicae ; (6): 735-738, 2016.
Article in English | WPRIM | ID: wpr-277911
ABSTRACT
Cushing's disease (CD) is a relatively rare disease,characterized by pathological hypercortisolism secondary to excessive adrenocorticotrophic hormone that is secreted by pituitary adrenocorticotrophic hormone adenoma or hyperplasia. In addition to the typical clinical symptoms such as moon face,buffalo hump,and central obesity,the CD patients may also experience mental disorders and cognitive dysfunction. This review mainly focuses on the cognitive state of CD patients,the mechanisms of cognitive impairment caused by high cortisol levels,and the imaging findings (especially magnetic resonance imaging) for the evaluation of cognitive functions.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Pituitary Neoplasms / Magnetic Resonance Imaging / Adenoma / Cognition / Cushing Syndrome / Pituitary ACTH Hypersecretion / Diagnosis / Cognitive Dysfunction / Hyperplasia Type of study: Diagnostic study Limits: Humans Language: English Journal: Acta Academiae Medicinae Sinicae Year: 2016 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pituitary Neoplasms / Magnetic Resonance Imaging / Adenoma / Cognition / Cushing Syndrome / Pituitary ACTH Hypersecretion / Diagnosis / Cognitive Dysfunction / Hyperplasia Type of study: Diagnostic study Limits: Humans Language: English Journal: Acta Academiae Medicinae Sinicae Year: 2016 Type: Article