Meta-analysis of the relationship between smoking and stomach cancer / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To explore the risk of stomach cancer associated with cigarette smoking.</p><p><b>METHODS</b>Meta-analysis was used to make formal summary statements about the relationship between smoking and stomach cancer. The results of the studies were analyzed by studied type(case-control study and cohort study) and gender(male and female). Homogeneity showed that random effect model should be selected to calculate the pooling relative risk (RR) and its corresponding 95% confidence interval (95%CI).</p><p><b>RESULTS</b>The total pooling RR(95%CI) was 2.14(1.12-4.06), while the total pooling RRs (95%CI) of male and female smoking with stomach cancer were 1.70 (1.34-2.14) and 1.83 (0.10-33.09), respectively.</p><p><b>CONCLUSIONS</b>Cigarette smoking is a risk factor for stomach cancer. Male smoking can increase risk of stomach cancer, however, the relationship between female smoking and stomach cancer should be studied further.</p>