Killing cell by granzyme / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 442-444, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-278143
ABSTRACT
Granzyme is an effector molecule of activated cytotoxic T cells and natural killer cells. It mainly mediates cell apoptosis. Its function could be explained by its molecular characteristics to some extent. Its cytotoxic effect is related to some other factors contributing to apoptosis induction. It deserves studying if perforin mediates entrance of granzyme into cells. As potential substrates of granzyme caspases and their substrates have been paid much attention to.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Membrane Glycoproteins
/
Serine Endopeptidases
/
Killer Cells, Natural
/
T-Lymphocytes, Cytotoxic
/
Apoptosis
/
Caspases
/
Allergy and Immunology
/
Granzymes
/
Pore Forming Cytotoxic Proteins
/
Perforin
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2002
Type:
Article
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