B cell activated co-receptor / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 436-439, 2002.
Article
in Chinese
| WPRIM
| ID: wpr-278145
ABSTRACT
B cell activated co-receptor plays important roles in linkage of innate and acquired humoral immune responses. CD21 molecule in the co-receptor complex is a receptor for C3dg and CD19 molecule enhances BCR signal transduction. CD21 also expresses on the surface of follicular dendritic cells, which mediates the long-term maintenance of antigens and is indispensable for maintaining the memory of B cells. B cell activated co-receptor also has an effect on the negative selection of B cells reactive to autoantigens.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Autoantigens
/
B-Lymphocytes
/
Receptors, Immunologic
/
Receptors, Complement 3d
/
Antigens, CD19
/
Allergy and Immunology
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2002
Type:
Article
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