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The multi-target drugs and their design / 药学学报
Acta Pharmaceutica Sinica ; (12): 282-287, 2009.
Article in Chinese | WPRIM | ID: wpr-278269
ABSTRACT
The reduce of bioactivity and augment of the side effect of single-target drugs is generated by the multi-factorial properties of the pathogenesis of disease, which could be solved by the multi-target drugs. The problems and its solution of the design of the multi-target drugs were discussed in this paper, at the same time, the design of the multi-target drugs by pharmacophore model method is presented.
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Drug Design / Signal Transduction / Drug Delivery Systems / Computer-Aided Design / Drug Combinations / Methods Type of study: Prognostic study Limits: Humans Language: Chinese Journal: Acta Pharmaceutica Sinica Year: 2009 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Drug Design / Signal Transduction / Drug Delivery Systems / Computer-Aided Design / Drug Combinations / Methods Type of study: Prognostic study Limits: Humans Language: Chinese Journal: Acta Pharmaceutica Sinica Year: 2009 Type: Article