Recent advance in the study of novel anti-tumor targets and drugs--aurora kinase and Pin1 / 药学学报
Acta Pharmaceutica Sinica
;
(12): 264-269, 2009.
Article
in Chinese
| WPRIM
| ID: wpr-278272
ABSTRACT
Malignant tumor, one of the most refractory diseases, plays a threaten role in human health, the therapy and research on malignant tumor have taken a long way to go. The anti-tumor drugs which are the essential therapy strategies upgrade with the development of new anti-tumor targets and the research on tumor pathogenesis. Aurora kinase and Pin1, the novel anti-tumor targets, maintain the important relationship with tumor. Many new compounds designed on these targets have excellent anti-tumor effects and also enter into phase I or phase II clinical trial.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Pharmacology
/
Piperazines
/
Naphthoquinones
/
Protein Serine-Threonine Kinases
/
Apoptosis
/
Peptidylprolyl Isomerase
/
Aurora Kinases
/
NIMA-Interacting Peptidylprolyl Isomerase
/
Metabolism
Limits:
Humans
Language:
Chinese
Journal:
Acta Pharmaceutica Sinica
Year:
2009
Type:
Article
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