Advances in Pathogenesis of Essential Thrombocythemia - Review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 287-291, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-278679
ABSTRACT
Essential thrombocythemia(ET) is one of the Ph chromosome-negative myeloproliferative neoplasms. Some studies discovered that the mutation of JAK2 V617F existed in 50%-70% patients with ET. Recently, many significant advances in researches about pathogenesis of ET, such as mutations of JAK2V617F, MPL, CALR and other related mutation; the epigenetic abnomalities in incidence of ET; the changes of bone marrow microenvironment of ET and the regulation of related cytokines were obtained. In this article, the advances of above mentioned aspects of ET are summarized.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2018
Type:
Article
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