Effect of puerarin on the expression of Hsp70 in the rats with cerebral injury induced by acute local ischemia / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 538-540, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-279118
ABSTRACT
<p><b>OBJECTIVE</b>To study the effect of puerarin on the expression of Hsp (heat shock protein) 70 in the rats with cerebral injury induced by acute local ischemia.</p><p><b>METHOD</b>Rat model of acute local cerebral ischemia was made by ligating middle cerebral artery. The Hsp70 expression in brain tissue was detected by SP method of immunohistochemistry.</p><p><b>RESULT</b>The expression of Hsp70 was significantly higher in puerarintreated rats than those in the rats with cerebral ischemia.</p><p><b>CONCLUSION</b>Puerarin can enhance the level of Hsp70 expression in the rats with cerebral injury induced by acute local ischemia.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Pharmacology
/
Plants, Medicinal
/
Brain Ischemia
/
Chemistry
/
Rats, Wistar
/
Neuroprotective Agents
/
HSP70 Heat-Shock Proteins
/
Infarction, Middle Cerebral Artery
/
Pueraria
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2005
Type:
Article
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