Study of huchang qingfei pellets on immune function in rats infected with Mycoplasma pneumoniae / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 366-369, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-279161
ABSTRACT
<p><b>OBJECTIVE</b>To study the effects and mechanism of Huchang Qingfei pellets on immune function in rats infected with mycoplasma pneumoniae.</p><p><b>METHOD</b>A rat model of mycoplasmal pneumonia (MP) was developed in repeated intranasal infectious routes and then the humoral and cellular immunocompetences were detected by radioimmunoassay, immune-turbidimetry and flow cytometry.</p><p><b>RESULT</b>The levels of serum IgG,IgM and IL-2, IL-6 were enhinced obviously, the complement C3 and TNF-alpha were decreased and the ratio of CD4+ /CD8+ was improved significantly in the Huchang groups as compared with MP model group.</p><p><b>CONCLUSION</b>Huchang Qingfei pellets can reinforce immune function via preventing both cellular and humoral immunity from depression in the rats with MP.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmacology
/
Plants, Medicinal
/
Pneumonia, Mycoplasma
/
Blood
/
Complement C3
/
Immunoglobulin G
/
Immunoglobulin M
/
Drugs, Chinese Herbal
/
Chemistry
/
Interleukin-6
Type of study:
Prognostic study
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2005
Type:
Article
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