Effect of Rhizoma pinelliae on vomiting in minks / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 277-279, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-279179
ABSTRACT
<p><b>OBJECTIVE</b>To study emetic and anti-emetic effects of Rhizoma pinelliae in minks.</p><p><b>METHOD</b>The emetic effect of raw pinellia 2 g kg(-1) (i.g.) was investigated. Three preparations of Rhizoma pinelliae (processed with ginger) were made by ethanol extraction, water extraction and water decoction respectively and their effects on emesis model induced by cisplatin (7.5 mg kg(-1), i.p.) or apomorphine (1.6 mg kg(-1), s.c.) were then studied; the effect of the decoction of ginger-processed Rhizoma pinelliae on rotation-induced emesis model in minks was also observed.</p><p><b>RESULT</b>The emesis was induced by raw pinellia in minks (P < 0.01); ginger-processed Rhizoma pinelliae, metoclopramide and ondansetron significantly inhibit the emesis induced by cisplatin and apomorphine (P < 0.05).</p><p><b>CONCLUSION</b>Ginger-processed Rhizoma pinelliae exhibits a anti-emetic effect in minks, which may be mediated by inhibiting the function of the vomiting center in central nervous system.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plants, Medicinal
/
Vomiting
/
Drugs, Chinese Herbal
/
Chemistry
/
Technology, Pharmaceutical
/
Ginger
/
Pinellia
/
Rhizome
/
Therapeutic Uses
/
Drug Therapy
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2005
Type:
Article
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