Relationship between autophagy and T2DM and intervention effect of traditional Chinese medicine / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 4351-4354, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-279235
ABSTRACT
Insulin resistance and insulin secretion deficiency are main machanisms in inducing type 2 diabetes mellitus (T2DM), and mitochondria damage plays an important role in them. Research shows that autophagy is a self-protective mechanism of cells, which plays an important role in maintaining the normal structure and function of pancreatic β cells and improving insulin resistance. Previous studies show that traditional Chinese medicine can regulate cell autophagy to influence β cells and insulin resistance, type 2 diabetes mellitus and its complications. Thus this review will talk about the process of the relationship between autophagy and T2DM and the intervention effect of traditional Chinese medicine.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Autophagy
/
Insulin Resistance
/
Drugs, Chinese Herbal
/
Cell Biology
/
Therapeutic Uses
/
Diabetes Mellitus, Type 2
/
Drug Therapy
/
Insulin-Secreting Cells
/
Insulin
/
Metabolism
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2015
Type:
Article
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