A Vision-Based System for Detecting and Analyzing the Freezing Response of Rats in Fearful Situations / 대한정신약물학회지
Korean Journal of Psychopharmacology
;
: 78-89, 2009.
Article
in Korean
| WPRIM
| ID: wpr-27930
ABSTRACT
OBJECTIVE:
The freezing response in rats has been used widely as an index of fear in threatening or stressful situations. Considering its importance in basic studies of affective disorders and in drug testing, it is necessary to develop a reliable, automated system for measuring the freezing response accurately.METHODS:
We developed the Vision-Based Analysis for Freezing (V-BAFF) system to analyze the freezing response in rats, based on several image-processing modules and motion classification schemes generated from our own experience. We compared the performance of V-BAFF with that of experienced human observers.RESULTS:
The level of freezing measured with V-BAFF was highly correlated with that measured by human observers.CONCLUSION:
We demonstrated that V-BAFF could yield a bias-free, accurate, and efficient measurement of freezing in rats.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Mood Disorders
/
Freezing
Limits:
Animals
/
Humans
Language:
Korean
Journal:
Korean Journal of Psychopharmacology
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS