Study on excretion of stilbene glycoside (THSG) and its beta-cyclodextrin inclusion / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2620-2623, 2010.
Article
in Chinese
| WPRIM
| ID: wpr-279387
ABSTRACT
The excretion characteristics of stilbene glycoside (THSG) and its beta-cyclodextrin inclusion in bile, urine and feces after oral administration to rats were studied. Bile for 24 h, urine and feces for 72 h were collected. The content of THSG was determined by HPLC-UV. The established HPLC-UV method was available for the analysis of THSG in excreta and corresponded to the requirement of biological sample analysis. After given THSG and its beta-cyclodextrin inclusion, the amount of prototype THSG in feces were 3.27% and 0.61%, meanwhile THSG in bile were 0.20% and 0.18%, respectively. Only a little THSG was found in urine. The result showed that beta-cyclodextrin inclusion reduced the fecal excretion of THSG. However, the characteristic of urinary and biliary excretion wasn't changed.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Stilbenes
/
Bile
/
Biological Transport
/
Inclusion Bodies
/
Chemistry
/
Administration, Oral
/
Chromatography, High Pressure Liquid
/
Rats, Sprague-Dawley
/
Bodily Secretions
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2010
Type:
Article
Similar
MEDLINE
...
LILACS
LIS