Elective neck dissection versus observation in early stage oral squamous cell carcinoma: recurrence and survival
Journal of the Korean Association of Oral and Maxillofacial Surgeons
;
: 358-364, 2016.
Article
in English
| WPRIM
| ID: wpr-27963
ABSTRACT
OBJECTIVES:
To evaluate the results of elective neck dissection versus those of observation in the treatment of early stage oral squamous cell carcinoma and to identify factors related to recurrence and survival. MATERIALS ANDMETHODS:
This was a retrospective study of 52 patients who underwent elective neck dissection and 27 who did not receive neck dissection.RESULTS:
In survival analyses, elective neck dissection showed a benefit in overall recurrence (P=0.027), especially in stage I patients (P=0.024). With regard to survival, the benefit was statistically insignificant (P=0.990). In multivariable analysis, overall recurrence was independently related to poor histologic grade (odds ratio [OR]=9.65, P=0.006), and cancer-specific death was independently related to advanced age (OR=6.3, P=0.022), higher clinical T stage (OR=15.2, P=0.01), and poorly differentiated histologic grade (OR=6.6, P=0.025).CONCLUSION:
Though there was lower recurrence in the elective neck dissection group, there were no statistically significant results on survival. The characteristics of the tumor itself, such as clinical T stage and poor histologic grade, may be more important in cancer-specific survival.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Neck Dissection
/
Recurrence
/
Mouth Neoplasms
/
Carcinoma, Squamous Cell
/
Survival Analysis
/
Survival Rate
/
Retrospective Studies
/
Epithelial Cells
/
Neck
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
Language:
English
Journal:
Journal of the Korean Association of Oral and Maxillofacial Surgeons
Year:
2016
Type:
Article
Similar
MEDLINE
...
LILACS
LIS