RANTES expression in venous ulceration of lower limbs / 南方医科大学学报
Journal of Southern Medical University
;
(12): 861-862, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-280079
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the expression of RANTES in venous ulceration.</p><p><b>METHODS</b>From patients with lower limb venous ulceration, patients with non-ulcerous venous insufficiency, and healthy individuals, peripheral blood was collected from the lower limb veins for measurement of RANTES mRNA using RT-PCR.</p><p><b>RESULTS</b>In the ulceration group, the expression of RANTES mRNA was significantly increased as compared with the other two groups (P<0.01). RANTES mRNA expression was also significant higher in the non-ulcerous group than the control group (P<0.01).</p><p><b>CONCLUSION</b>High expression of RANTES mRNA may be one of the important mechanisms of venous ulceration.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Varicose Ulcer
/
Venous Insufficiency
/
Blood
/
RNA, Messenger
/
Chemokine CCL5
/
Reverse Transcriptase Polymerase Chain Reaction
/
Genetics
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2008
Type:
Article
Similar
MEDLINE
...
LILACS
LIS