Rapid differential diagnosis of thalassemia trait and iron-deficiency anemia with stepwise regression analysis / 南方医科大学学报
Journal of Southern Medical University
;
(12): 609-611, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-280135
ABSTRACT
<p><b>OBJECTIVE</b>To establish a method for rapid differential diagnosis of thalassemia trait (TT) and iron-deficiency anemia (IDA) using stepwise regression analysis.</p><p><b>METHODS</b>Stepwise regression equation was established for differential diagnosis of TT and IDA according to the red cell index, and the accuracy of the differential diagnosis was evaluated using blind analysis.</p><p><b>RESULTS</b>The accuracy of this equation for differential diagnosis of TT and IDA was 86.82%. The sensitivity, specificity and Youden's index in prediction of TT and IDA were 94.29%, 79.66%, 73.9 and 76.92%, 90.52%, and 67.4%, respectively.</p><p><b>CONCLUSION</b>The stepwise regression equation using the red cell index is concise, rapid, and sensitive in differential diagnosis of TT and IDA, and can be well applicable in clinical practice.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thalassemia
/
Blood
/
Double-Blind Method
/
Regression Analysis
/
Reproducibility of Results
/
Sensitivity and Specificity
/
Anemia, Iron-Deficiency
/
Diagnosis
/
Diagnosis, Differential
Type of study:
Controlled clinical trial
/
Diagnostic study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Journal of Southern Medical University
Year:
2008
Type:
Article
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