Research into the Pathogenicity of Enterovirus 71 / 病毒学报
Chinese Journal of Virology
; (6): 192-196, 2015.
Article
in Zh
| WPRIM
| ID: wpr-280274
Responsible library:
WPRO
ABSTRACT
Enterovirus 71 (EV71) is a major causative agent of hand, foot and mouth disease (HFMD). belongs to family Picornaviridae, genus Enterovirus, species A. EV71 infection usually affects subjects aged <5 years. HFMD caused by EV71 infection is usually mild in children. However, in some cases EV71 infection can lead to severe neurogenic disease and even death. EV71 infection has caused epidemic worldwide (especially in the Asia Pacific). HFMD caused by EV71 has become a major public-health prol lem across the Asia Pacific. In EV71 infection, the pathogenesis is determined by viral and host factor, Here, we review research on host susceptibility and how EV71 suppresses immune and intracellular ri
Full text:
1
Index:
WPRIM
Main subject:
Physiology
/
Virology
/
Virulence
/
Virus Replication
/
Enterovirus A, Human
/
Virus Attachment
/
Genetics
/
Hand, Foot and Mouth Disease
Limits:
Animals
/
Humans
Language:
Zh
Journal:
Chinese Journal of Virology
Year:
2015
Type:
Article