Correlation between periodontal disease and coronary atherosclerotic heart disease / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 169-172, 2006.
Article
in Chinese
| WPRIM
| ID: wpr-281239
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the correlation between coronary atherosclerotic heart disease (CAD) and periodontal disease (PD).</p><p><b>METHOD</b>Forty-five patients with CAD (CAD group) and 40 patients without CAD (control group) were compared with their pathological changes of periodontal tissues and inflammatory markers [high sensitive C reactive protein (hsCRP), interleukin-1beta (IL-1beta), and tumor necrosis factor-alpha (TNF-alpha)].</p><p><b>RESULTS</b>Univariate analysis showed that the prevalence of PD was 84.44% in CAD group and 22.50% in control group (P < 0.01). The levels of hsCRP, IL-1beta, and TNF-alpha were (5.75 +/- 1.26) mg/L, (10.32 +/- 2.96) ng/L, and (9.17 +/- 2.14) ng/L in CAD group and (1.13 +/- 0.73) mg/ L, (2.87 +/- 1.45) ng/L, and (5.84 +/- 1.96) ng/L in control group (P < 0.01). Gingival index and plaque index were statistically different between two both groups (P < 0.01). Logistic regression analysis showed that in addition to pulse pressure and low density lipoprotein cholesterol, periodontal disease index was a higher risk factor of CAD. Its relative risk was 1.217 (95% CI was 1.120-1.805, P < 0.05).</p><p><b>CONCLUSION</b>PD can cause CAD. The improvement of public oral health plays an important role in the prevention and treatment of CAD.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pathology
/
Periodontal Diseases
/
Blood
/
Coronary Artery Disease
/
C-Reactive Protein
/
Case-Control Studies
/
Periodontal Index
/
Dental Plaque Index
/
Risk Factors
/
Interleukin-1
Type of study:
Etiology study
/
Observational study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
Chinese
Journal:
Acta Academiae Medicinae Sinicae
Year:
2006
Type:
Article
Similar
MEDLINE
...
LILACS
LIS