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Influence of chronic HBV infection in the husband on the outcome of IVF-ET treatment / 南方医科大学学报
Journal of Southern Medical University ; (12): 1827-1829, 2007.
Article in Chinese | WPRIM | ID: wpr-281530
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the outcome of in vitro fertilization and embryo transfer (IVF-ET) in couples with the husband positive for chronic infection of hepatitis B virus (HBV).</p><p><b>METHODS</b>This study involved 102 infertile couples receiving IVF-ET with the husbands(but not the wives) positive for hepatitis B surface antigen (HBsAg), and another 204 couples negative for HBsAg receiving the treatment served as the control group. The cumulative embryo score, fertilization rate, cleavage rate, rate of good quality embryos, implantation rate, clinical pregnancy rate, first trimester and late miscarriage rates, delivery rate, and neonatal malformation rate were recorded and compared between the two groups.</p><p><b>RESULTS</b>Between the HBsAg-positive and the control groups, the cumulative embryo score (52.8-/+18.7 vs 55.4-/+16.9), insemination rate (66.9% vs 66.1%), cleavage rate (97.6% vs 97.2%), rate of good quality embryos (34.0% vs 37.1%), implantation rate (40.9% vs 34.6%), clinical pregnancy rate (56.9% vs 50%), first trimester miscarriage rate (6.9% vs 5.9%) and late pregnancy miscarriage rate (8.6% vs 4.9%), delivery rate (40.2% vs 43.6%) and neonatal malformation rate (0 vs 0) were all similar (P>0.05;).</p><p><b>CONCLUSION</b>Chronic HBV infection in the husband might not affect the outcome of IVF-ET treatment.</p>
Subject(s)
Full text: Available Index: WPRIM (Western Pacific) Main subject: Blood / Pregnancy Outcome / Fertilization in Vitro / Case-Control Studies / Hepatitis B, Chronic / Embryo Transfer / Hepatitis B Surface Antigens Type of study: Observational study Limits: Female / Humans / Male / Pregnancy Language: Chinese Journal: Journal of Southern Medical University Year: 2007 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Blood / Pregnancy Outcome / Fertilization in Vitro / Case-Control Studies / Hepatitis B, Chronic / Embryo Transfer / Hepatitis B Surface Antigens Type of study: Observational study Limits: Female / Humans / Male / Pregnancy Language: Chinese Journal: Journal of Southern Medical University Year: 2007 Type: Article