Chemical constituents in Flos Sophorae Carbonisatus / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the chemical constituents of lipid-soluble and water-soluble extracts in Flos Sophorae Carbonisatus.</p><p><b>METHOD</b>The compounds were isolated by means of solvent extraction and column chromatography, and their structures were determined by spectral analysis.</p><p><b>RESULT</b>Two compounds from petroleum ether extract and ten from n-BuOH extract were isolated and identified as sophoradiol (1), beta-sitosterol (2), 3 beta, 22 beta, 24-trihydroxy-olean-12-ene (soyasapogenol B) (3), daucosterol (4), kaikasaponin I (5), quercetin (6), isorhamnetin (7), 2-O-methyl-insitol (8), isorhamnetin-3-O-rutinoside (9), isoquercitrin (10), orobol-7-O-beta-D-glucoside (11), rutin (12), respectively.</p><p><b>CONCLUSION</b>Compound 3, 8-11 were isolated from Flos Sophorae Carbonisatus for the first time. The results could be basic foundation for further study on processing mechanism of Flos Sophorae Carbonisatus.</p>