Natural products in clinical trials: antibacterial and antifungal agents

Li HAN; Dan ZHENG; Xue-Shi HUANG; Shi-Shan YU; Xiao-Tian LIANG; Li HAN; Dan ZHENG; Xue-Shi HUANG; Shi-Shan YU; Xiao-Tian LIANG

Natural products in clinical trials: antibacterial and antifungal agents / 药学学报

Li HAN; Dan ZHENG; Xue-Shi HUANG; Shi-Shan YU; Xiao-Tian LIANG; Li HAN; Dan ZHENG; Xue-Shi HUANG; Shi-Shan YU; Xiao-Tian LIANG.

Acta Pharmaceutica Sinica ; (12): 236-244, 2007.

Article in Chinese | WPRIM | ID: wpr-281914

ABSTRACT

ABSTRACT

Natural products have played an important role in drug discovery. Today, therapeutics from natural origin count for about 70% of the worldwide human therapeutic sales. For anti-infective treatment even higher figures are reported. This review describes antibacterial and antifungal natural products, semi-synthetic natural products and natural product derived compounds undergoing clinical evaluation or registration from 1998 to end of 2005. In addition, natural product derived drugs launched since 1998 are also discussed in this review.

Subject(s)

Humans; Anti-Bacterial Agents; Chemistry; Pharmacology; Antifungal Agents; Chemistry; Pharmacology; Biological Products; Chemistry; Pharmacology; Drug Resistance, Microbial; Drugs, Investigational; Chemistry; Pharmacology; Echinocandins; Chemistry; Pharmacology; Molecular Structure; Polyenes; Chemistry; Pharmacology

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pharmacology / Polyenes / Biological Products / Drug Resistance, Microbial / Molecular Structure / Drugs, Investigational / Chemistry / Echinocandins / Anti-Bacterial Agents / Antifungal Agents Limits: Humans Language: Chinese Journal: Acta Pharmaceutica Sinica Year: 2007 Type: Article

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