Cerebral angiography and MR perfusion images in patients with ischemic cerebral vascular disease / 中华医学杂志(英文版)
Chin. med. j
; Chin. med. j;(24): 1687-1691, 2002.
Article
in En
| WPRIM
| ID: wpr-282108
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the value of perfusion MR imaging and angiographic evidence of collateral circulation in symptomatic patients with ischemic cerebrovascular diseases (ICVD).</p><p><b>METHODS</b>Cerebral angiography and perfusion MR were performed in 16 patients with symptoms of ICVD. Qualitative perfusion maps were calculated for regional cerebral blood volume (rCBV) and mean transit time (MTT).</p><p><b>RESULTS</b>A total of 27 lesions were seen on the perfusion MR maps (6 infarcts and 21 ischemic lesions) and most of them (26/27) showed a prolonged MTT. MTT is sensitive to the presence of ischemic lesions, but not sufficient in distinguishing infarct from ischemia. All of the infarcts showed a decreased rCBV, while most of the ischemic lesions showed a normal or increased rCBV. When collateral circulation was identified on angiography, most ischemic lesions were not infarcts and had a normal or increased rCBV. The absence of angiographically identifiable cerebral collaterals may not always result in an infarct; 50% had decreased rCBV. Despite the absence of angiographic collaterals, the other half had normal or increased rCBV.</p><p><b>CONCLUSION</b>Cerebral angiographic evidence of collateral circulation is important in identifying a favorable outcome in patients with ICVD. However, a lesion with a normal or increased rCBV suggests a sufficient collateral circulation even without angiographic collaterals. Perfusion images may be a potentially useful adjunctive tool in the prediction of the outcome of ICVD, particularly where no apparent collateral macrocirculation is seen on CA.</p>
Full text:
1
Index:
WPRIM
Main subject:
Magnetic Resonance Imaging
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Cerebral Angiography
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Cerebral Infarction
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Brain Ischemia
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Cerebrovascular Circulation
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Collateral Circulation
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Diagnosis
Type of study:
Diagnostic_studies
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Prognostic_studies
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Qualitative_research
Limits:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
Language:
En
Journal:
Chin. med. j
Year:
2002
Type:
Article