Isolation and identification of the ligustilide compounds from the root of Angelica sinensis / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To find out substance basis of pharmacological activities of Angelica sinensis.</p><p><b>METHOD</b>Chromatographic methods were used to isolate the chemical components, and spectroscopic methods were used to identify their structures.</p><p><b>RESULT</b>Five compounds were isolated from the ethanol extract of the roots of Angelica sinensis. Their structures were identified as (Z)-ligustilide, (Z)-6,7-epoxyligustilide, (Z)-6,7-cis-dihydroxyligustilide, (E)-6,7-cis-dihydroxy-ligustilide and 11-angeloylsenkyunolide F.</p><p><b>CONCLUSION</b>11-angeloylsenkyunolide F was obtained from Angelica sinensis for the first time.</p>